Everything you need to know about thiamine: the key to health and energy

What is thiamine?
Thiamine, also known as vitamin B1, is a water-soluble B vitamin that plays a key role in carbohydrate metabolism and energy production in the body (1). Since the body cannot store it in large quantities, it needs regular intake through food or supplements (2).

The role of thiamine in the body

• Energy Metabolism: Thiamine is a cofactor for enzymes involved in glucose metabolism, which means it directly affects the production of ATP – the basic energy molecule in cells (1).

• Nervous system: Vitamin B1 is necessary for the transmission of nerve impulses and the functioning of neurotransmitters. Deficiency can cause fatigue, irritability, and difficulty concentrating (3).

• Heart and muscles: Thiamine supports the proper functioning of the heart muscle and muscle tissue by enabling efficient energy metabolism (4).

• Mental health: Research shows that adequate thiamine levels reduce the risk of depression and improve mood (5).

Thiamin deficiency
Since thiamine is water-soluble, it is quickly excreted from the body. Deficiency may occur in:

• Unbalanced diet (eg too many refined carbohydrates) (2).

• Excessive alcohol consumption, which interferes with the absorption of thiamine (3).

• Chronic diseases (e.g. diabetes, heart failure) where thiamine requirements are greater (4).

Deficiency symptoms include fatigue, irritability, poor concentration, muscle weakness and, in severe cases, diseases such as beri-beri and Wernicke-Korsakoff syndrome (5).

Benefits of Thiamine Supplementation

• More energy: Supports glucose metabolism and reduces fatigue (1).

• Better mood: Contributes to the stable functioning of the nervous system (5).

• Heart Support: Proven to improve heart function in heart failure patients (4).

• Brain protection: Helps prevent neurological complications in deficiency (3).

Why liposomal form?
Liposomal technology enables better absorption of thiamine compared to classic tablets.

• Protection from degradation: Lipsosomes protect thiamine from degradation in the digestive tract (6).

• Faster effect: Nutrient is transferred more efficiently into the bloodstream (6).

• Suitable for people with absorption disorders: The liposomal form is particularly useful for chronic diseases or digestive problems (6).

Conclusion

Thiamine is a key vitamin for health, energy and well-being. Since the body does not store it, it is essential to take care of its regular intake through food or supplements. The liposomal formulation represents a modern approach that provides better absorption and more effective action (1–6).

📚 Literature

1. Lonsdale, D. (2006).A review of the biochemistry, metabolism and clinical benefits of thiamin. Journal of Evidence-Based Complementary & Alternative Medicine.

2. Whitfield, K.C., et al. (2018). Thiamine deficiency disorders: diagnosis, prevalence, and a global perspective. Annals of the New York Academy of Sciences.

3. Sechi, G., Serra, A. (2007). Wernicke's encephalopathy: new clinical settings and recent advances in diagnosis and management. Lancet Neurology.

4. Schoenenberger, A.W., et al. (2012). Thiamine supplementation in heart failure: clinical evidence and mechanisms. International Journal of Cardiology.

5. Benton, D., Donohoe, R. (1999). The effects of vitamin supplementation on mood and cognitive performance. Psychological Medicine.

6. Allen, T.M., Cullis, P.R. (2013). Liposomal drug delivery systems: from concept to clinical applications. Advanced Drug Delivery Reviews.